If you use a multi-monitor or ultra-wide setup, press Windows Key + P and change the project mode to PC screen only to see if the game launches on a single primary monitor. 6. Switch Graphic APIs (DirectX vs. Vulkan)

Even on modern Windows, some older components are required. Run DXSETUP.exe as an administrator from the game's installation folder or download the DirectX End-User Runtimes directly from Microsoft.

Complete Guide to Fixing "Serious Sam 3 Cannot Set Display Mode" Error

While well-intentioned, users have reported that the following actions are for this specific error: